崔業波; 包海鷹; 李玉
吉林農業大學中藥材學院; 吉林農業大學中藥材學院; 吉林農業大學中藥材學院 長春130118; 長春130118; 長春130118

【中文摘要】 建立靈苓神顆粒劑的制備工藝和質量控制方法,并通過藥理實驗研究其鎮靜安神的藥理作用。靈芝和茯神配伍,采用擠出制粒法制得靈苓神顆粒。通過小鼠的催眠實驗和影響小鼠自主活動的藥理實驗研究靈苓神的藥理作用。靈苓神能顯著的增加小鼠的入睡個數和減少小鼠的活動時間。結論:靈苓神顆粒劑具有鎮靜安神的作用。

【英文摘要】 To set up preparation technology and quality control methods of Ling-ling Shen Granule and research on its sedative and hypnotic effect by pharmacological experiment.Ling-ling Shen containing the mainly Ganoderma and Poria with hostwood is preparared through using the extrusion method,and studied the pharmacological effect of Ling-ling Shen by the hypnotic experiment and affecting the time of mice's active behaviors experiment.Ling-ling Shen can obviously reduce the active behaviors of mice and increase the number of hypnotic mouse.Ling-ling Shen Granule possesses obviously sedative and hypnotic effect in mice.

【中文關鍵詞】 靈苓神顆粒劑; 靈芝; 茯神; 鎮靜藥和催眠藥; 小鼠; 苯巴比妥鈉
【英文關鍵詞】 Ling-ling Shen Granule; Ganoderma lucidum(Curtis:Fr.) Karst.; Poria with hostwood; Hypnotics and sedatives; Mice; Phenobarbital sodium

【文獻出處】 中國食用菌,Edible Fungi of China,編輯部郵箱,2007年05期 【DOI】CNKI:SUN:ZSYJ.0.2007-05-014