朱繼紅; 李鐵民; 陳穎; 楊瀟; 叢娜; 初洪文; 李昱
遼寧大學(xué)生命科學(xué)系; 遼寧大學(xué)生命科學(xué)系; 遼寧大學(xué)生命科學(xué)系; 遼寧大學(xué)生命科學(xué)系; 遼寧大學(xué)生命科學(xué)系; 遼寧大學(xué)生命科學(xué)系; 遼寧大學(xué)生命科學(xué)系 沈陽110036 ; 沈陽110036 ; 沈陽110036 ; 沈陽110036 ; 沈陽110036 ; 沈陽110036 ; 沈陽110036

【中文摘要】 靈芝干膏、破壁和未破壁靈芝孢子粉對小鼠脾重/體重比值無顯著影響;可顯著提高淋巴細(xì)胞轉(zhuǎn)化率,但三者的藥效在統(tǒng)計(jì)學(xué)上無顯著差異;這三種藥物成分可顯著增強(qiáng)小鼠腹腔巨噬細(xì)胞酸性磷酸酶(ACP)的活性,靈芝干膏增強(qiáng)ACP酶活性維持的時間較長,靈芝孢子粉則在一定時間范圍內(nèi)酶活較高,破壁率越高,所需劑量越小,達(dá)到最高酶活所需時間越短。

【英文摘要】 The immunoregulation effect of the dry extract, sporederm-broken(SB) and sporedem-nonbroken(SN) spore powder of Ganoderma lucidum on the mice was studied. And the spleen/body weight rate, lymphocyte transformation rate and the activity of acid phosphatase(ACP) of the abdominal cavity macrophages of the mice were measured. The experiment results showed that these ingredients couldn't significantly affect the spleen/body weight rate, but could significantly improve the percentage of lymphocyte transformation, though there were no obvious statistics differences among them, and that the dry extract, SB and SN spore powder of G.lucidum could significantly enhance the ACP activity of the macrophages of the mice, merely the dry extract could kept ACP activity at a higher degree for a relatively longer period, but for the spore powder, the higher ACP activity could only be kept during a definite period of time, and the higher the SB ratio, the shorter the time and the smaller the dose needed t...更多o reach the maximum enzyme activity.  還原

【中文關(guān)鍵詞】 靈芝干膏; 靈芝孢子粉; 淋巴細(xì)胞轉(zhuǎn)化; 巨噬細(xì)胞; 酸性磷酸酶
【英文關(guān)鍵詞】 Dry extract of Ganoderma lucidum; Ganoderma lucidam spore powder; Lymphocyte transformation; Macrophage; Acid phosphatase(ACP)
【基金】遼寧省教育廳推廣計(jì)劃基金項(xiàng)目"靈芝系列產(chǎn)品的研制與開發(fā)"(20023288)的部分內(nèi)容

【文獻(xiàn)出處】 食用菌學(xué)報(bào),Acta Edulis Fungi,編輯部郵箱,2004年04期 【DOI】CNKI:SUN:SYJB.0.2004-04-005